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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH1L
All Species:
21.82
Human Site:
S2462
Identified Species:
48
UniProt:
Q9NR48
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR48
NP_060959.2
2969
332790
S2462
G
I
I
S
Y
K
D
S
S
R
Q
A
L
A
A
Chimpanzee
Pan troglodytes
XP_513861
2964
332149
F2457
G
I
I
S
Y
K
D
F
S
R
Q
A
L
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851926
2974
332800
S2467
G
I
I
S
Y
K
D
S
S
R
Q
A
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99MY8
2958
331289
S2451
G
I
I
S
Y
R
D
S
S
Q
Q
T
L
A
A
Rat
Rattus norvegicus
NP_001101159
2918
326454
S2411
G
I
I
S
Y
K
D
S
S
Q
Q
A
L
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511389
1395
154154
P962
L
Q
P
T
L
T
P
P
K
V
G
G
A
G
L
Chicken
Gallus gallus
XP_422858
2954
330578
S2447
S
I
I
A
Y
K
D
S
S
R
Q
A
L
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692254
2962
327377
S2401
M
I
T
S
Y
K
D
S
S
G
Q
P
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW15
2226
246247
L1793
K
I
A
S
Y
V
Q
L
V
E
I
L
G
D
S
Honey Bee
Apis mellifera
XP_001122948
2180
246181
T1747
S
D
P
I
D
L
S
T
I
D
Q
C
I
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784903
3312
363645
P2809
A
V
C
T
Y
R
N
P
S
G
Q
S
L
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.1
N.A.
91.7
91.2
N.A.
21.5
79.9
N.A.
40.9
N.A.
26.1
26
N.A.
27.3
Protein Similarity:
100
99.6
N.A.
97
N.A.
95.3
94.4
N.A.
31.8
89.2
N.A.
53
N.A.
42.2
43.9
N.A.
43.3
P-Site Identity:
100
93.3
N.A.
100
N.A.
80
93.3
N.A.
0
86.6
N.A.
73.3
N.A.
20
6.6
N.A.
33.3
P-Site Similarity:
100
93.3
N.A.
100
N.A.
93.3
100
N.A.
6.6
93.3
N.A.
73.3
N.A.
26.6
20
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
0
0
46
10
73
64
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
10
0
64
0
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
46
0
0
0
0
0
0
0
0
19
10
10
10
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
55
10
0
0
0
0
10
0
10
0
10
0
10
% I
% Lys:
10
0
0
0
0
55
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
10
10
0
10
0
0
0
10
73
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
19
0
0
0
10
19
0
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
19
82
0
0
0
0
% Q
% Arg:
0
0
0
0
0
19
0
0
0
37
0
0
0
0
0
% R
% Ser:
19
0
0
64
0
0
10
55
73
0
0
10
0
0
10
% S
% Thr:
0
0
10
19
0
10
0
10
0
0
0
10
0
0
10
% T
% Val:
0
10
0
0
0
10
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _